Recent Advances in Cancer Treatment: A Review
Keywords:Cancer therapy, chemotherapy, biomarkers, targeted therapy, virotherapy, antiagiogenesis, monoclonal antibodies
The landscape of cancer treatment has dramatically changed over the last four decades. The age when surgery and radiotherapy were the only effective way to fight tumour growth has ended. A complex scenario where the molecular features of tumours seem to be the cornerstone of any therapy is now emerging. Small molecule drugs are being intensively pursued as new anticancer therapeutics. Cancer treatment has benefited significantly from progress in understanding how to target kinases with small molecules that were found to be correlated with the disease because many kinases have been found to be intimately involved in the processes leading to tumour cell proliferation and survival. This review provides an overview on the different approaches to cancer treatment including the role of classic cancer therapies that is - surgery, radiation, chemotherapy and endocrine therapy and then an up-date on the novel, up-growing therapies of the current targeted therapy - including new monoclonal antibodies, small molecules, antiangiogenics and viral therapy. Finally, few words about the development of new biomarkers and how it should rule and determine the future of therapeutic research in cancer.
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